Lizzy Caplan and Michael Sheen Starring in Showtime’s ‘Masters of Sex’

Lizzy Caplan has made many a fan through memorable appearances on premium cable shows, from the hilarious and gone-too-soon Party Down to her V-juice-addicted traveler on True Blood. This fall, she has top billing in one: Masters of Sex, a new Showtime series in which she stars alongside Michael Sheen.

Masters of Sex centers on the lives of William Masters and Virginia Johnson (played by Sheen and Caplan, respectively), two real-life researchers who, for decades, pioneered key research on human sexuality and relationships. Naturally, the first teaser for the show focuses on these questions, with some discussion about key matters, such as faking orgasms. The show will premiere on Showtime on September 29th, 2013, and in the meantime, you can catch the very short, inquiry-packed trailer below.

Showtime Debuts ‘Masters Of Sex’ Trailer

It’s true, 2013 will bring us a reality show about drunk 19-year-olds riding ATVs in the mud. But click over to Showtime and there’s a new drama about sexuality researchers, Masters Of Sex, starring Michael Sheen and Lizzy Caplan.

Sheen plays Dr. William Masters, an OB-GYN teaching at a Midwestern college, and Caplan is his research assisant, Virginia Johnson. The series will be based on the nonfiction book Masters Of Sex, by Thomas Maier, and explains how these two became the foremost sexuality experts in a time before Dr. Ruth, Loveline, and Dan Savage. In addition to researching the sex lives of others, Masters and Johnson became romantically entangled with each other.

Showtime hasn’t yet announced when Masters Of Sex will begin its 12-episode run. The network will also debut Ray Donovan, a drama starring Liev Shrieber about a "fixer" in Los Angeles (which is also seen in the trailer below).

Contact the author of this post at Jessica.Wakeman@Gmail.com. Follow me on Twitter.